A better blood test has been developed for the early diagnosis of sarcoidosis

A better blood test has been developed for the early diagnosis of sarcoidosis

blood test
blood test

Lophilia Samavati, MD, is a professor of internal medicine, molecular medicine and genetics at Wayne State University School of Medicine.

A research project led and supported by the National Institutes of Health (NIH) has developed a rapid and inexpensive diagnostic tool for sarcoidosis. , a chronic inflammatory disease characterized by the growth of small tumors called granulomas in the lungs and other organs.

A device that uses a simple blood test allows the option of more invasive diagnostic tests often used to diagnose the disease. The findings were published in the American Journal of Respiratory and Critical Care Medicine.

Although the exact cause of sarcoidosis is unknown, researchers suspect that it is an immune disorder triggered by a group of specific antigens, which are foreign substances that normally trigger the body’s immune response. According to previous research, 8-11 out of 100,000 people in the United States are diagnosed with sarcoid each year.

To identify antigens and identify those associated with sarcoidosis, scientists collected lung fluid samples and blood cells from patients with pulmonary sarcoidosis and extracted genetic material.

Using a combination of molecular techniques, researchers identified two newly described disease-specific antigen biomarkers that bind antibodies only in sarcoidosis-positive patients.

He then devised a more specific blood test that required less blood. To validate the test, researchers compared blood samples from 386 people, including sarcoidosis patients, tuberculosis patients, lung cancer patients, and healthy individuals. The researchers confirmed that their test could distinguish sarcoidosis patients from patients with other respiratory diseases.

“More trials need to be completed before this screening method is ready for clinical use, but it will become a reality in a few years,” Samavati said.

groundbreaking work is a great example of how scientific research can address major health challenges,” said Wayne State University Vice President for Research M. Esimenari said. of people with sarcoidosis.”

A blood test is a laboratory analysis of your blood. You may have blood tests to determine how well you are managing a condition such as diabetes or high cholesterol. You can take these for routine checkups or when you are sick.

blood test
blood test

Blood tests are very common. Healthcare providers order them to:

Find out how well your organs are working, such as your kidneys, liver, heart or thyroid

Help diagnose diseases like cancer, diabetes, coronary heart disease and HIV/AIDS

Find out if your medication is working to make you feel better

Identify bleeding or clotting disorders

Find out if your immune system is having trouble fighting infection

Diagnose anemia such as iron deficiency anemia, pernicious anemia, aplastic anemia, or hemolytic anemia

Identify hemoglobin variants such as hemoglobin S, C or E, which are more common in people of African, Mediterranean or Southeast Asian background.

Monitor chronic health conditions and diseases

Detect health problems in their early stages

You have the right to know why the blood test was ordered. If you’re not sure why he or she wants to test you, ask your healthcare provider.

blood test
blood test

Types of blood tests

General blood test:

Complete blood count is also known as CBC

Blood chemistry test

Blood enzyme test

Blood test for heart disease risk

Blood tests provide a lot of information to your healthcare provider. He or she can see if certain components of your blood are within normal limits. But in most cases, blood tests are part of the information your healthcare provider needs to diagnose a medical condition. You may also need some other types of tests.

Blood test preparation

For most types of blood tests, you don’t need to prepare. These tests determine what your blood looks like under normal conditions.

Some blood tests do not require a short (fast) meal before the blood test. That means don’t eat or drink anything after midnight before the exam. These tests are often scheduled early in the morning.

Your healthcare provider will let you know if you need to fast before the blood test.

process

To test your blood, a technician called a phlebotomist uses a needle to draw a blood sample. If you are uncomfortable looking at needles, tell the technician. It will help you feel more comfortable. You can look away and bring a family member or friend to distract you during the process.

In most cases, the sample is taken from a vein in your arm. You can sit or lie down. You may be asked to clench your fists. A technician will place a rubber band on your arm. If he finds a vein, the technician will clean the area and then insert a needle. You may feel a slight shock.

After the technician has removed enough blood, he removes the needle and places an adhesive bandage over the area. You may be asked to apply firm pressure to the area to stop the bleeding.

After the process

Your blood sample will be sent to a laboratory. A trained technician looks up the information ordered by the healthcare provider. This may take a day, a week or more. Contact your health care provider’s office again to learn about the results.

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